Ossification and hypertrophy of ligamentum flavum at thoracic spine.

نویسندگان

  • Mubarak Hussain
  • Riaz Ahmed Raja
  • Asadullah Makhdoom
چکیده

BACKGROUND Hypertrophy of the ligamentum flavum is a pathological condition that causes neurological symptom (radiculopathy and / or myelopathy) and usually occurs in the thoracic,2 less frequently in the cervical spine that commonly involves thoracic spine. This study was conducted to analyse the clinical presentation and outcome of surgery of ossified ligamentum flavum at thoracic spine. METHODS This case series was conducted at Department of Neurosurgery, Liaquat University of Medical and Health Sciences Jamshoro, from January 2010 to December 2012. Patients who presented with thoracic myelopathy due to ossified ligamentum flavum were included. All the patients, after detailed history, clinical examination and radiological investigation under went decompressive laminectomy at the appropriate level. Pre-operative, post-operative and neurolog'ifti', 06 months follow up was recorded. The patients having thoracic myelopathy due to other causes were excluded from the study. SPSS-10 was used to analyse the data. RESULTS A total of 15 patients were admitted and operated (9 males, 6 females. (M:F ratio of 1.5:1). The majority of patients were in 6th decade. Backache and lower limb weakness was the presenting feature. Overall improvement in preoperative neurological status was seen in 9 (60%) patients. Neurology remained unchanged in 4 (26.6%) patients and worsened in 2 (13.3%) patients. CONCLUSION The disease is common in 5th and 6th decade. Preoperative duration of symptoms significantly correlates with recovery.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Simultaneous Diffuse Idiopathic Hyperostosis, Ossification of the Posterior Longitudinal Ligament and Ligamentum Flavum

Background and Importance: A 60-year-old diabetic man with simultaneous diffuse idiopathic hyperostosis, massive ossification of the posterior longitudinal ligament and cervical and higher part of thoracic ligamentum flavum is reported in this article. Such comorbidity rarely occurs. Case Presentation: The patient’s chief complaint was sensation abnormalities without gait disturbance or ...

متن کامل

Ossification of the ligamentum flavum in cervical and thoracic spine. Report of three cases.

Ossification of ligamentum flavum (LF) is a pathological condition that causes neurological symptoms and usually occurs in the thoracic spine and less frequently in the cervical spine. Symptomatology usually involves occipital headache in the early stage, neck pain and later sensory disturbances of upper and lower extremities, gait disturbance, restricted cervical movement and tetraparesis. Her...

متن کامل

Chest Discomfort Secondary to Ossification of the Ligamentum Flavum of the Thoracic Spine: A Case Report

Symptomatic thoracic ossification of the ligamentum flavum is rare, and a modality for its treatment has not yet been fully established; most reported patients complained of myelopathy. Herein, the authors will report on an extremely rare presentation of thoracic ossification of the ligamentum flavum, along with clinical outcomes. The patient complained of chest discomfort and myelopathy sympto...

متن کامل

Myelopathy due to ossification or calcification of the ligamentum flavum: radiologic and histologic evaluations.

The clinical, radiologic, and histologic features of ossification and calcification of the ligamentum flavum were studied in 18 patients. Ossification (15 patients) usually occurred in the lower thoracic spine in men of various ages, while calcification (three patients) was found exclusively in the cervical region of older women. Histologic examinations of ossification showed mature lamellar bo...

متن کامل

Ossification process involving the human thoracic ligamentum flavum: role of transcription factors

INTRODUCTION Ossification of the ligamentum flavum (OLF) of the spine is associated with serious neurologic compromise, but the pathomechanism of this process remains unclear. The objective of this study was to investigate the pathomechanism of the ossification process, including the roles of various transcriptional factors in the ossification of human thoracic ligamentum flavum. METHODS Sect...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of Ayub Medical College, Abbottabad : JAMC

دوره 26 3  شماره 

صفحات  -

تاریخ انتشار 2014